Three Clemson players are officially suspended for Saturday’s Cotton Bowl between the No. 2 Tigers and No. 3 Notre Dame Fighting Irish.

It was announced Monday that DT Dexter Lawrence, TE Braden Galloway and OL Zach Giella were suspended for the game after testing positive for a banned substance (ostarine). The suspensions were confirmed Thursday as all three players’ “B samples” again tested positive. Barring any appeal, the three cannot play in any games for 365 days.

The headliner of the trio is Lawrence. A potential first-round NFL Draft pick, the junior’s suspension will almost certainly only apply to the College Football Playoff (Saturday and a possible appearance in the championship game for Clemson).

Clemson AD Dan Radakovich issued a statement on the news:

“This evening, Clemson Athletics received confirmation from the NCAA of suspensions for tight end Braden Galloway, offensive lineman Zach Giella and defensive tackle Dexter Lawrence, all three of whom will be unavailable for Saturday’s game against Notre Dame. The athletic department will have no further comment on the matter this evening as it considers all of our options, including appeals.”