We’ve reached the deadline to declare early for the NFL draft.

As is the case every season, the SEC is full of third-year players ready to earn a paycheck to play football.

Let’s take a look at the five most significant losses in the SEC due to early entry. These are not the five best players headed to the NFL, but rather the five whose absence will make the biggest impact on their respective programs.

NO. 5: ARKANSAS G DENVER KIRKLAND

The Razorbacks lost a quartet of offensive players with eligibility remaining, including running backs Alex Collins and Jonathan Williams as well as tight end Hunter Henry.

Along with senior quarterback and three-year starter Brandon Allen, that’s a huge amount of talent, production and experience for offensive coordinator Dan Enos to replace.

But this team’s identity is in its offensive line. And with Sebastian Tretola and Mitch Smothers on the way out, Kirkland’s decision means that Arkansas will be replacing the entire left side of that unit.

Kirkland did not get mentioned on any All-SEC lists. But he had a chance to be the best run-blocking guard in the SEC in 2016. With a new quarterback behind him and no Collins or Williams, the Hogs would’ve loved that asset.

NO. 4: FLORIDA S KEANU NEAL

Florida is losing an SEC-high five players to early entry.

We’ve known since about halfway through the 2013 season that this would mark the end of Vernon Hargreaves III’s college career. Plus, Jalen Tabor (and Quincy Wilson) is back, and he arguably had a better ’15 season than Hargreaves. Alex McCalister is a loss, but the Gators have plenty of bodies along the defensive line.

Neal, though, was not a player many Gators fans expected to lose as recent as a few months ago. He made 96 tackles in an injury-shortened season and now projects as a second-day NFL draft pick. One of the hardest hitters in the SEC, he’ll be missed on a defense that’s losing a significant amount of talent.

Considering the team’s quarterback quandary, Florida would like at least one more season of fielding a shut-down secondary, and without Neal that only gets more difficult.

NO. 3: ALABAMA RB DERRICK HENRY

Normally it’s a good thing when the Tide’s top running back leaves because it allows a talented backup to get carries, which in turn helps the team sell a three- or four-year plan to the nation’s top prep backs.

Mark Ingram gives way to Trent Richardson, who gives way to Eddie Lacy, who gives way to T.J. Yeldon, who gives way to Henry.

In all of those instances, the second player already had proven himself. Henry is the first back in a long time at Alabama who didn’t play as part of a significant tag team at running back.

Prior to 2015, Alabama lost an unusual amount of depth at the position due to injury, transfer and suspension. Now senior Kenyan Drake is following Henry out of Tuscaloosa.

Bo Scarbrough, who shares some physical similarities with Henry but tore his ACL prior to the season, and Damien Harris, a former five-star recruit who looked just OK as a true freshman, are left behind. Alabama must also run the ball without center Ryan Kelly, who also is headed to the NFL, and with yet another new quarterback.

No longer will the offensive formula be as easy as handing the ball to Henry 35 times a game with occasional third-down throws to Calvin Ridley.

NO. 2: OLE MISS WR LAQUON TREADWELL

The Rebels will not be hurting for pass-catching targets in 2016.

Evan Engram, Quincy Adeboyejo, Damore’ea Stringfellow and Markell Pack, among others, will help Chad Kelly to another big statistical season.

But Treadwell is one of the most NFL-ready SEC receivers of the last decade, right there with Amari Cooper and Odell Beckham Jr. At 6-foot-2 and 210 pounds, he’s got a catch radius of someone four inches taller. He fights for every football, is as physical as any receiver and got much more explosive in 2015.

Despite coming off a horrific leg injury, Treadwell averaged a career-best 14.1 yards per catch and scored 11 touchdowns.

He’s just not the kind of receiver you replace with someone else, even in a productive system, and expect the same results.

NO. 1: SOUTH CAROLINA WR PHAROH COOPER

His 66 receptions more than doubled the Gamecocks’ second-leading receiver in 2015. His quarterback rating the last two years was as good as any South Carolina signal-caller. Oh yeah, and he occasionally returned punts and ran the ball.

Cooper accounted for 10 of the team’s 29 touchdowns in ’15 as one of the only dynamic options on a frustrating offense.

He may not be the best player entering the NFL draft early, nor the highest drafted. He’s listed at just 5-foot-11. But for what he meant to the Gamecocks, outside of a few outgoing quarterbacks, it’s hard to think of a more impactful single SEC offensive player in 2015.

Will Muschamp’s offense is going to be under all sorts of scrutiny, considering his failure to oversee a productive unit on that side of the ball at Florida. Cooper would’ve made for one heck of an elixir in Muschamp’s first season in Columbia.

Also Considered: Mississippi State WR De’Runnya Wilson, Mississippi State DT Chris Jones, Ole Miss LT Laremy Tunsil, Auburn LT Shon Coleman, Florida CB Vernon Hargreaves III, Arkansas RB Alex Collins