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SEC Football

Friday Forecast: SDS Staff picks 5 Week 1 matchups against the spread

Ethan Stone

By Ethan Stone

Published:


The SEC regular season kicked off Thursday night with Mizzou‘s blowout win over Arkansas-Pine Bluff. With the season now officially underway, our crew here at Saturday Down South is back with 5 Week 1 picks against the spread.

Let’s jump right in.

(All odds are via DraftKings, finalized on Thursday, Sept. 3. Point spreads might not necessarily reflect current odds.)

Week 1 Picks ATS

Hereโ€™s how the SDS crew picked 5 SEC games in Week 1 (against the spread).

Looking to make some picks for Week 1? Check out our guide on the best sports betting apps to score a sign-up bonus at your book of choice.

2025 Season Records

  • Spenser Davis: 2-1
  • Andy Olson: 1-2
  • Adam Spencer: 0-3
  • Ethan Stone: 2-1

East Carolina at Alabama (-28.5)

Spenser Davis: Under Kalen DeBoer, Alabama has absolutely decimated these tune-up opponents early in the season. In 2024, the Tide beat Western Kentucky 63-0. In 2025, they dismantled ULM 73-0. ECU has a rivalry game against Appalachian State in Week 2 thatโ€™s much more winnable โ€” Iโ€™m not sure what kind of fight the Pirates will put up in Week 1 against an Alabama offense that will be looking for style points. PICK: Alabama -28.5 

Andy Olson: I know rosters change more than ever year-to-year in the portal era, but Blake Harrell led ECU to a 9-4 season with a bowl win last year. I donโ€™t think this game will be truly close, but I can see the Pirates covering 41-14. Iโ€™m intrigued by the Keelon Russell hype, but itโ€™s still a first career start for a second-year QB. PICK: East Carolina +28.5

Adam Spencer: I went 0-3 last week, so Iโ€™ve already got a hole to climb out of. So Iโ€™ll echo Spenser here and say Kalen DeBoer once again takes care of business as a heavy favorite. Alabama could cover this spread by halftime if all goes well. PICK: Alabama -28.5

Ethan Stone: East Carolina is in the higher tier of โ€œcupcakeโ€ opponents Alabama could have faced, but the Pirates are still outmatched all over the field. Also, Kalen DeBoerโ€™s Tide have outscored G6 opponents 286-23 across his first 2 seasons in Tuscaloosa โ€“ 16 of those points came from Alex Goleshโ€™s South Florida Bulls in 2024. Ant, meet boot. PICK: Alabama -28.5

Baylor vs. Auburn (-7.5) (Atlanta, GA)

Spenser Davis: Weโ€™ll see what Byrum Brown looks like in SEC play, but I expect him to look just fine against Baylor in Week 1. This should be an Auburn-heavy crowd in Atlanta and I think the Tigers will have a significant talent advantage over the Bears at most positions on the field. Pick: Auburn -7.5

Andy Olson: The half point is bugging me here. Iโ€™m confident Auburn wins by 7, and 8+ feels more likely than 6 points or fewer. I like the comfort of Byrum Brown with Alex Goleshโ€™s offense. And in the DJ vs. DJ matchup when Baylor has the ball, I think itโ€™s advantage Durkin. PICK: Auburn -7.5

Adam Spencer: If Auburn doesnโ€™t win this game by 10+ points, itโ€™s a huge red flag. Baylor has a coach on one of the hottest seats in college football (outside of Tallahassee) and a QB who was literally quoted as saying he thought God forgot about him during his time at Florida. DJ Lagway could end up being solid for Baylor, but Auburn canโ€™t let him get into a groove in Week 1. PICK: Auburn -7.5

Ethan Stone: Iโ€™ve seen a lot of people point to Auburnโ€™s large makeup of G6 transfers as a positive for Baylor here, but the Bears arenโ€™t exactly stacked in the trenches. Auburn is the more talented team and more than anything, I trust the Tigers to score. While DJ Lagway has potential, that confidence isnโ€™t really there yet. PICK: Auburn -7.5

Clemson at LSU (-10)

Spenser Davis: I so badly want to buy low on Clemson, but I just canโ€™t do it โ€” I donโ€™t believe in Chad Morris as offensive coordinator and Iโ€™m not sure the Tigers have a quality starting quarterback. Iโ€™m not sure LSU will have a great Year 1 under Lane Kiffin, but I do think thereโ€™s some blowout potential here. PICK: LSU -10

Andy Olson: I feel like itโ€™s always an adventure with Lane Kiffin teams covering the spread in big games. Iโ€™d be stunned by a Clemson upset outright, but Iโ€™m going to take the fightinโ€™ Dabos to keep this one within single digits. PICK: Clemson +10

Adam Spencer: Reading the words โ€œChad Morris as offensive coordinatorโ€ in Spenserโ€™s answer sent shivers down my spine. LSU by a million. PICK: LSU -10

Ethan Stone: The funniest possible outcome here is Clemson winning by 3 touchdowns. Could you imagine? Anyway… PICK: LSU -10

FAU at Florida (-26.5)

Spenser Davis: I donโ€™t want to lean too much on trends, but I donโ€™t show a significant edge here for either team. Since thatโ€™s the case, Iโ€™ll point this out โ€” Jon Sumrall is 32-17-1 (FBS regular-season games only) against the spread in his head coaching career. Florida has a huge talent edge here and should be eager to prove it. PICK: Florida -26.5

Andy Olson: As excited as I am to watch the Buster Faulkner offense with Jadan Baugh, Vernell Brown III, Dallas Wilson and Eric Singleton, Iโ€™m not sure about covering 27 points in the debut. Aaron Philo has limited experience, and itโ€™s a rebuilt offensive line that hasnโ€™t played together before, which could lead to some Week 1 miscues. I donโ€™t think a Florida win will ever be in doubt, but I could see this being something like 41-17. PICK: FAU +26.5

Adam Spencer: If Florida just keeps handing the ball to Jadan Baugh, this should be fairly easy to cover. FAU is No. 113 in ESPNโ€™s Football Power Index. This isnโ€™t the version of the Owls that Lane Kiffin made relevant several years ago. Give me the Gators in a big-time blowout. PICK: Florida -26.5

Ethan Stone: This is the same pick as Alabama -28.5, in my mind. This may be Jon Sumrallโ€™s first game at Florida, but his Gators are bigger and faster than the Owls. No need to overthink this one. PICK: Florida -26.5

Louisville vs. Ole Miss (-6.5) (Nashville, TN)

Spenser Davis: I think Louisville is live to win this game outright. Ole Miss has a lot of new faces on offense and Pete Golding is still relatively untested as an SEC head coach. I think this game should be much closer to a pick ’em even with Ole Missโ€™s talent edge on paper. PICK: Louisville +6.5ย 

Andy Olson: The Ole Miss offense will likely take a step back following the departures of Lane Kiffin and Charlie Weis Jr., but new OC John David Baker has Ole Miss familiarity and some play-calling experience, so I think Trinidad Chambliss and Kewan Lacy are in for another big season. We saw in the CFP that Pete Golding knows how to get the Rebels fired up for a big game. PICK: Ole Miss -6.5

Adam Spencer: Louisville doesnโ€™t technically need to win this game to have a path to the Playoff. The rest of the Cardinalsโ€™ schedule is a cakewalk. Iโ€™m going to buy into the Pete Golding era. The Rebels have 2 top-5 offensive players in the entire conference in Trinidad Chambliss and Kewan Lacy. That duo goes off and Ole Miss wins by a touchdown. PICK: Ole Miss -6.5

Ethan Stone: Thereโ€™s been so much talk about Ole Missโ€™s date against Lane Kiffin and LSU that a lot of folks (hopefully not Ole Miss!) are forgetting about a tough season opener against Jeff Brohm and the Louisville Cardinals. That alone makes me want to take a talented Louisville squad here. Not to mention, Brohm is in his element in games like this. PICK: Louisville +6.5


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Ethan Stone

Ethan Stone is a Saturday Down South News Editor and an advocate for the return of the Seattle Supersonics.

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